2F6Z: Protein tyrosine phosphatase 1B with sulfamic acid inhibitors

PDB ID: 2F6ZDownload
MMDB ID: 36866
PDB Deposition Date: 2005/11/29
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 2F6Z: monomeric; determined by author
Molecular Components in 2F6Z
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Phosphatase, Non-receptor Type 1
(Gene symbol: PTPN1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
MAGNESIUM IONMAGNESIUM ION
2
4
CHLORIDE IONCHLORIDE ION
3
1
{3(S)-METHYLCARBAMOYL-2-[3-(3-SULFOAMINO-PHENYL)-PROPIONYL]-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-7-YL}-SULFAMIC ACID{3(S)-METHYLCARBAMOYL-2-[3-(3-SULFOAMINO-PHENYL)-PROPIONYL]-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-7-YL}-SULFAMIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303